Jun 4, 2014
It is a massive increase in the risk of developing lung cancer,"
The research, published in the journal Nature, found the gene could double the likelihood of getting lung cancer.孔聖堂中學中六
And some men and women faced a far greater risk, a team at the Institute of Cancer Research in London said.
Cancer Research UK suggested drugs targeted at breast cancer may work in some lung cancers.
The links between variants of the BRCA genes and breast cancer are well established - a diagnosis led Hollywood actress Angelina Jolie to have a preventative double mastectomy - but it has also been linked with an increased risk of other cancers affecting women such as ovarian cancer and prostate cancer in men.
The study compared the genetic codes of people with and without lung cancer.
Smokers have 40 times the chance of developing lung cancer, but those with a BRCA2 mutation were nearly 80 times more likely, the analysis showed.
A quarter of those carrying the mutation, and who also smoke, will go on to develop lung cancer, the research team said.
"It is a massive increase in the risk of developing lung cancer," said Prof Richard Houlston from the team.
"There is a subset of the population who are at very significant risk.
"The most important thing is reducing smoking; it is so bad for other diseases, as well as [increasing] the risk of lung cancer."
Mutations to the BRCA genes stop DNA from repairing itself effectively.
"In the context of smoking there is such an enormous amount of DNA damage that any loss of DNA repair is going to be an issue," Prof Houlston added.
The discovery could mean treatments that are being developed for breast cancer may also work in some cases of lung cancer孔聖堂中學
"We've known for two decades that inherited mutations in BRCA2 made people more likely to develop breast and ovarian cancer, but these new findings show a greater risk of lung cancer too, especially for people who smoke," said Prof Peter Johnson, Cancer Research UK's chief clinician.
"Importantly this research suggests that treatments designed for breast and ovarian cancer may also be effective in lung cancer, where we urgently need new drugs.
"But, with or without one of these genetic flaws, the single most effective way to reduce the risk of lung cancer is to be a non-smoker."孔聖堂中學好唔好
Posted at 08:42 pm by nseew
May 23, 2014
The New York Times then reported that the companies .
Initial reports suggested that the NSA did in fact extract the data via special equipment they had installed on the companies' computers which acted as a "back door".
However, the tech firms denied they provided "direct access".
The New York Times then reported that the companies had created the digital equivalent of "locked mailboxes" - secure areas on their networks onto which they copied the requested files for the agency to inspect.home improvement
However, Google later denied this in an interview with Wired magazine.
It said it had complied with court-ordered requests by either sending data over secure FTP (file transfer protocol) - an encrypted transmission sent from its computers to the authorities' - or by physically handing over the information "in person".Multi-touch Panel
Other tech firms have not been as specific.
On 29 June the Washington Post published additional slides which it said showed the NSA obtained at least some of the information from the FBI, adding that the bureau had indeed placed "government equipment" on the private property of participating companies.
The newspaper added that as a result the NSA was able to carry out real-time surveillance through Prism. It said this included live notifications of when a target logged on or sent an email as well as the ability to monitor a voice or text chats as they happened.designer sunglasses women
Posted at 08:47 pm by nseew
Mar 9, 2014
Whilst it is too soon to speculate about any connection between these stolen passports and the missing plane, it is clearly of great concern that any passenger was able to board an international flight using a stolen passport listed in Interpol databases," the Secretary General of international police agency Interpol, Ronald Noble, said in a statement.Interactive
He said no checks of Interpol's database had been made for either passport between the time they were stolen and the departure of the flight, and expressed frustration that few of Interpol's 190 member countries "systematically" search the database.
Malaysia's Transport Minister Hishammuddin Hussein said all angles were being examined in the search for the what happened, but he added: "The main thing here for me and for the families concerned is that we find the aircraft."Lafite
The passengers on the flight were of 14 different nationalities. Two-thirds were from China, while others were from elsewhere in Asia, North America and Europe.
Malaysia Airlines is the country's national carrier, and one of Asia's largest fleets, flying nearly 37,000 passengers daily to some 80 destinations worldwide.
Correspondents say the route between Kuala Lumpur and Beijing has become more and more popular as Malaysia and China increase tradeinteractive digital signage
Posted at 11:45 pm by nseew
Feb 10, 2014
HE poets make Fame a monster
THE poets make Fame a monster. They describe her in part finely and elegantly, and in part gravely and sententiously. They say, look how many feathers she hath, so many eyes she hath underneath; so many tongues; so many voices; she pricks up so many ears. This is a flourish. There follow excellent parables; as that, she gathereth strength in going; that she goeth upon the ground, and yet hideth her head in the clouds; that in the daytime she sitteth in a watch tower, and flieth most by night; that she mingleth things done, with things not done; and that she is a terror to great cities. But that which passeth all the rest is: They do recount that the Earth, mother of the giants that made war against Jupiter, and were by him destroyed, thereupon in an anger brought forth Fame. For certain it is, that rebels, figured by the giants, and seditious fames and libels, are but brothers and sisters, masculine and feminine. But now, if a man can tame this monster, and bring her to feed at the hand, and govern her, and with her fly other ravening fowl and kill them, it is somewhat worth. But we are infected with the style of the poets. To speak now in a sad and serious manner: There is not, in all the politics, a place less handled and more worthy to be handled, than this of fame. We will therefore speak of these points: What are false fames; and what are true fames; and how they may be best discerned; how fames may be sown, and raised; how they may be spread, and multiplied; and how they may be checked, and laid dead. And other things concerning the nature of fame. Fame is of that force, as there is scarcely any great action, wherein it hath not a great part; especially in the war. Mucianus undid Vitellius, by a fame that he scattered, that Vitellius had in purpose to remove the legions of Syria into Germany, and the legions of Germany into Syria; whereupon the legions of Syria were infinitely inflamed. Julius Caesar took Pompey unprovided, and laid asleep his industry and preparations, by a fame that he cunningly gave out: Caesar’s own soldiers loved him not, and being wearied with the wars, and laden with the spoils of Gaul, would forsake him, as soon as he came into Italy. Livia settled all things for the succession of her son Tiberius, by continual giving out, that her husband Augustus was upon recovery and amendment, and it is an usual thing with the pashas, to conceal the death of the Great Turk from the janizaries and men of war, to save the sacking of Constantinople and other towns, as their manner is. Themistocles made Xerxes, king of Persia, post apace out of Grecia, by giving out, that the Grecians had a purpose to break his bridge of ships, which he had made athwart Hellespont. There be a thousand such like examples; and the more they are, the less they need to be repeated; because a man meeteth with them everywhere. Therefore let all wise governors have as great a watch and care over fames, as they have of the actions and designs themselves…
Posted at 07:39 pm by nseew